Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 401
interventional 281
Observational 109
Registry 11

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 112
Other 37
Device 36
Drug|placebo 31
Procedure 15
Biological 11
Device|Other 6
Diagnostic Test 5
Drug|Other 5
Biological|placebo 4
Device|Procedure 3
Combination Product 2
Other|Procedure 2
Behavioral 1
Behavioral|Device|Procedure 1
Biological|Device|Drug 1
Biological|Drug 1
Biological|Other 1
Combination Product|Other 1
Combination Product|placebo 1
Device|Drug|Other 1
Device|Other|Procedure 1
Device|placebo 1
Dietary Supplement 1
Drug|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
France 46
United States 41
Germany 20
NA 17
Italy 16
Canada 12
China 12
Egypt 11
Thailand 10
India 9
Brazil 8
Denmark 4
Indonesia 4
Chile 3
Mexico 3
Spain 3
Tunisia 3
United States|Canada 3
Austria 2
Belgium 2
Czechia 2
Greece 2
Korea, Republic of 2
Netherlands 2
Qatar 2
Sweden 2
Switzerland 2
United Kingdom 2
Australia 1
Australia|Austria|Brazil|Colombia|France|Germany|Israel|New Zealand|Norway|Singapore|South Africa|Spain|Switzerland|United Kingdom 1
Australia|Belgium|Canada|Czech Republic|Finland|France|Spain 1
Australia|Brazil|New Zealand 1
Australia|Denmark|New Zealand|Saudi Arabia|United Kingdom 1
Australia|France 1
Austria|Belgium|France|Germany|Israel|Italy|Netherlands|Portugal|United Kingdom 1
Austria|Belgium|Germany|Italy|Latvia|Norway|Spain|United Kingdom 1
Austria|Belgium|Spain 1
Austria|Germany 1
Belgium|Czechia|Denmark|Finland|France|Italy|Netherlands|Norway|Spain|Sweden|Switzerland 1
Belgium|Denmark 1
Belgium|France|Germany|Netherlands 1
Belgium|France|Netherlands 1
Belgium|France|Netherlands|Spain 1
Belgium|France|Spain 1
Belgium|Lithuania 1
Czech Republic 1
Czechia|Slovakia 1
Denmark|Finland 1
Denmark|Finland|Iceland|Norway 1
Denmark|Finland|Norway|Sweden 1
Denmark|Germany 1
Finland 1
Finland|Switzerland 1
France|Germany|South Africa|United Kingdom 1
France|Guadeloupe 1
Japan 1
Puerto Rico 1
Saudi Arabia 1
Taiwan 1
Turkey 1
United States|Australia|Belgium|Canada|Finland|France|Germany|New Zealand|Switzerland|United Kingdom 1
United States|Belgium|Canada|Denmark 1
United States|Brazil|Canada|Greece|India|Pakistan|Philippines 1
Zambia|Zimbabwe 1

Sites per Study

Site_count Study_Count
1 189
2 21
3 9
4 4
5 2
6 5
7 5
8 4
9 3
10 1
11 5
13 2
14 1
15 1
16 3
18 3
20 2
21 2
22 1
26 1
30 2
31 1
32 2
33 1
34 1
40 2
47 1
48 1
52 2
57 1
61 1
70 1
115 1

Phase

Phase Study_Count
N/A 117
Phase 2 52
Phase 3 47
Phase 4 36
Phase 2/Phase 3 16
Phase 1 7
Phase 1/Phase 2 6

Number of Arms

Number_of_Arms Count_of_Studies
1 40
2 188
3 22
4 6
5 1
7 3
NA 21

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 7.0000 9.00000 12.0000 2.0000 20.000 26.0000 9.0000
1st Qu. 40.0000 21.50000 31.7500 23.0000 63.000 101.2500 42.0000
Median 80.0000 29.00000 94.0000 48.5000 90.000 246.5000 90.0000
Mean 198.5897 58.14286 258.8333 107.1346 134.625 429.3478 340.0833
3rd Qu. 184.0000 58.00000 287.5000 119.5000 165.500 543.2500 348.7500
Max. 3044.0000 210.00000 990.0000 636.0000 380.000 1818.0000 3800.0000

Trial Group Type

group_type Group_Count
Experimental 237
Active Comparator 141
Placebo Comparator 62
No Intervention 46
Other 37
NA 21
Sham Comparator 9

Intervention Model

intervention_model Study_Count
Parallel Assignment 209
Single Group Assignment 51
Crossover Assignment 12
Factorial Assignment 6
NA 2
Sequential Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 225
Diagnostic 19
Prevention 8
Supportive Care 8
Basic Science 7
Other 6
NA 5
Health Services Research 2
Screening 1

Observational Studies

Studies by Country

Country Study_Count
France 26
United States 21
Germany 9
NA 9
United Kingdom 6
China 3
Italy 3
Netherlands 3
Singapore 3
Canada 2
Finland 2
Poland 2
Spain 2
Taiwan 2
Argentina 1
Austria|Belgium|Czechia|Denmark|France|Germany|Greece|Hungary|Israel|Italy|Lithuania|Netherlands|Poland|Portugal|Russian Federation|Spain|Sweden|Switzerland|United Kingdom 1
Belgium|France|Germany|Italy|Netherlands 1
Belgium|Spain|Switzerland 1
Canada|Sweden 1
Czechia 1
Denmark 1
Egypt 1
Hungary 1
Indonesia 1
Mexico 1
Norway 1
Switzerland 1
Thailand 1
Turkey 1
United States|Canada 1

Sites per Study

Site_count Study_Count
1 91
2 2
3 7
7 2
9 2
10 1
12 1
13 1
24 1
97 1

Enrollment Metrics

Measure Observational
Min 1.0000
1st Qu 38.0000
Median 80.0000
Mean 787.7248
3rd Qu 200.0000
Max 50000.0000

Observation Model

observational_model Study_Count
Cohort 68
Case-Only 22
Case-Control 7
Other 7
NA 4
Case Control 1

Time Perspective

time_perspective Study_Count
Prospective 88
Retrospective 16
Cross-Sectional 3
Other 1
NA 1

Registries

Studies by Country

Country Study_Count
France 2
Thailand 2
United States 2
Brazil 1
India 1
Korea, Republic of 1
Norway 1
Switzerland 1

Sites per Study

Site_count Study_Count
1 9
12 1
90 1

Enrollment Metrics

Measure Registries
Min 40.000
1st Qu 165.000
Median 458.000
Mean 1346.727
3rd Qu 768.000
Max 10000.000

Registry Model

observational_model Study_Count
Cohort 9
Other 2

Time Perspective

time_perspective Study_Count
Prospective 9
Cross-Sectional 1
Other 1

Follow-up

target_duration Study_Count
1 Year 3
1 Day 2
6 Months 2
1 Month 1
2 Days 1
4 Weeks 1
90 Days 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT02768740 Hydrocortisone 50 mg Every 6 Hours Compared to Hydrocortisone 300 mg Per Day in Treatment of Septic Shock. https://ClinicalTrials.gov/show/NCT02768740 Completed Association Niçoise de Réanimation Médicale 2010-05-31
NCT04459572 As an Early Indicator Biomarker of Prognosis and Mortality in Children With Sepsis and Septic Shock: suPAR https://ClinicalTrials.gov/show/NCT04459572 Completed Ege University 2019-09-27
NCT03677102 Fluids in Septic Shock (FISSH) https://ClinicalTrials.gov/show/NCT03677102 Recruiting McMaster University 2021-07-01
NCT03400787 Latera RCT - Latera vs. Sham Control for Lateral Nasal Valve Collapse https://ClinicalTrials.gov/show/NCT03400787 Active, not recruiting Spirox, Inc. 2019-02-01
NCT02053675 Hemodynamic Effects of Vasopressin in Early Septic Shock Stage https://ClinicalTrials.gov/show/NCT02053675 Completed Federal University of São Paulo 2013-04-30
NCT03380507 Evaluation of Hydrocortisone, Vitamin C and Thiamine for the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT03380507 Recruiting Hamad Medical Corporation 2019-04-30
NCT03378466 Heparin Anticoagulation in Septic Shock https://ClinicalTrials.gov/show/NCT03378466 Recruiting University of Manitoba 2020-12-31
NCT02754193 Effects of Induced Moderate HYPOthermia on Mortality in Cardiogenic Shock Patients Rescued by Veno-arterial ExtraCorporeal Membrane Oxygenation (ECMO) https://ClinicalTrials.gov/show/NCT02754193 Active, not recruiting Central Hospital, Nancy, France 2019-07-20
NCT03366220 Resuscitation With Plasma in Surgical and Trauma Patients With Septic Shock https://ClinicalTrials.gov/show/NCT03366220 Enrolling by invitation The University of Texas Health Science Center, Houston 2021-03-26
NCT03344627 Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients https://ClinicalTrials.gov/show/NCT03344627 Completed Mahidol University 2018-11-30
NCT03338569 Vitamin C and Septic Shock https://ClinicalTrials.gov/show/NCT03338569 Recruiting University of Minnesota 2020-06-20
NCT02468063 To Assess the Efficacy of Early Introduction of a Combination of Low Dose Vasopressin Analogue in Addition to Noradrenaline as a Vasopressor in Patients of Cirrhosis With Septic Shock https://ClinicalTrials.gov/show/NCT02468063 Completed Institute of Liver and Biliary Sciences, India 2017-05-31
NCT03251170 Ketamine Versus Fentanyl for Induction of Anesthesia in Septic Shock https://ClinicalTrials.gov/show/NCT03251170 Completed Cairo University 2019-12-25
NCT03222154 EFFECTS OF SHOCK WAVE THERAPY IN WOMEN WITH PAIN IN TRAPÉZIO MUSCLE https://ClinicalTrials.gov/show/NCT03222154 Completed Estácio Ponta Negra 2016-10-01
NCT03208257 Esmolol to Control Adrenergic Storm in Septic Shock- ROLL-IN 2 https://ClinicalTrials.gov/show/NCT03208257 Recruiting Intermountain Health Care, Inc. 2020-12-31
NCT03201575 REmote Ischemic COnditioning in Septic Shock https://ClinicalTrials.gov/show/NCT03201575 Active, not recruiting Hospices Civils de Lyon 2019-08-31
NCT03193164 Neuromuscular Electrical Stimulation and Septic Shock https://ClinicalTrials.gov/show/NCT03193164 Recruiting University of Sao Paulo 2019-07-01
NCT03158948 Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of 3 Doses of MOTREM in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT03158948 Completed Inotrem 2018-06-13
NCT03149315 Inhibition of Anaphylaxis by Ibrutinib https://ClinicalTrials.gov/show/NCT03149315 Completed Ann & Robert H Lurie Children’s Hospital of Chicago 2018-11-14
NCT03137446 Restrictive Intravenous Fluids Trial in Sepsis https://ClinicalTrials.gov/show/NCT03137446 Completed Rhode Island Hospital 2018-03-30
NCT03120637 Evaluating in Cirrhotics With Refractory Vasoplegia the Effect of Methylene Blue https://ClinicalTrials.gov/show/NCT03120637 Completed Institute of Liver and Biliary Sciences, India 2018-01-10
NCT03104140 Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock https://ClinicalTrials.gov/show/NCT03104140 Completed Cairo University 2018-04-01
NCT03093987 Critical Care Ultrasound Oriented Shock Treatment in ICU https://ClinicalTrials.gov/show/NCT03093987 Completed West China Hospital 2017-10-28
NCT03092245 Vasculopathic Injury and Plasma as Endothelial Rescue in Septic Shock (SHOCK) Trial https://ClinicalTrials.gov/show/NCT03092245 Active, not recruiting Rigshospitalet, Denmark 2020-04-01
NCT03085758 Treatment of Patients With Early Septic Shock and Bio-Adrenomedullin(ADM) Concentration > 70 pg/ml With ADRECIZUMAB https://ClinicalTrials.gov/show/NCT03085758 Completed Adrenomed AG 2019-12-20
NCT03078712 Early Goal Directed Therapy Using a Physiological Holistic View. The ANDROMEDA-SHOCK Study https://ClinicalTrials.gov/show/NCT03078712 Completed Pontificia Universidad Catolica de Chile 2018-03-15
NCT03066375 Respiratory Variations For Predicting Fluid Responsiveness 2 https://ClinicalTrials.gov/show/NCT03066375 Completed University Hospital, Lille 2015-05-31
NCT03066362 Respiratory Variations for Predicting Fluid Responsiveness https://ClinicalTrials.gov/show/NCT03066362 Completed University Hospital, Lille 2014-01-31
NCT03065751 Plasmaexchange in Early Septic Shock https://ClinicalTrials.gov/show/NCT03065751 Recruiting Hannover Medical School 2021-01-31
NCT03038503 What Should be the Next Vasopressor for Severe Septic Shock? Methylene Blue or Terlipressin https://ClinicalTrials.gov/show/NCT03038503 Recruiting Ramathibodi Hospital 2018-12-31
NCT03029169 Propafenone Versus Amiodarone in Septic Shock https://ClinicalTrials.gov/show/NCT03029169 Recruiting Charles University, Czech Republic 2021-06-30
NCT03026777 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation https://ClinicalTrials.gov/show/NCT03026777 Completed Louisiana State University Health Sciences Center in New Orleans 2018-01-31
NCT02204852 Co-administration of Iloprost and Eptifibatide in Septic Shock Patients https://ClinicalTrials.gov/show/NCT02204852 Completed Rigshospitalet, Denmark 2016-08-31
NCT02982876 Airway Stents for Excessive Dynamic Airway Collapse https://ClinicalTrials.gov/show/NCT02982876 Enrolling by invitation Beth Israel Deaconess Medical Center 2020-12-31
NCT02972827 Monitoring Devices in Prediction of Fluid Responsiveness in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02972827 Recruiting Santa Barbara Cottage Hospital 2020-05-31
NCT02971670 Amendment of rTSST-1 Variant Vaccine Phase 1 Clinical Trial https://ClinicalTrials.gov/show/NCT02971670 Completed Biomedizinische Forschungs gmbH 2016-03-31
NCT02937961 Early Versus Late Sustained Low Efficiency Dialysis in Critically Ill Cirrhotics With Septic Shock and Acute Kidney Injury https://ClinicalTrials.gov/show/NCT02937961 Recruiting Institute of Liver and Biliary Sciences, India 2019-03-01
NCT02919267 Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms https://ClinicalTrials.gov/show/NCT02919267 Completed Laval University 2016-12-31
NCT02885168 Modulation of Vasoreactivity in Septic Shock: Impact of Recombinant Protein C https://ClinicalTrials.gov/show/NCT02885168 Completed Central Hospital, Nancy, France 2009-04-30
NCT02870946 The Effect of Simultaneous Renal Replacement Therapy on Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock Patients https://ClinicalTrials.gov/show/NCT02870946 Recruiting Beijing Anzhen Hospital 2019-09-30
NCT02856191 Study on the Frequency of de Novo Atrial Fibrillation in Septic Shock in Medical Intensive Care https://ClinicalTrials.gov/show/NCT02856191 Completed Centre Hospitalier Universitaire Dijon 2011-09-30
NCT02854969 Satisfaction of Patient With Anaphylaxis in the Use of a Medical Device https://ClinicalTrials.gov/show/NCT02854969 Completed Adan Medical Innovation, SL 2017-07-18
NCT02848144 Pediatric Immune Response to Infectious Shock https://ClinicalTrials.gov/show/NCT02848144 Completed Hospices Civils de Lyon 2018-08-04
NCT02841241 Esmolol Infusion for Patients With Septic Shock and Persistent Tachycardia https://ClinicalTrials.gov/show/NCT02841241 Completed Intermountain Health Care, Inc. 2017-03-31
NCT02835157 Balanced Salt Solutions vs. Normal Saline in Children With Septic Shock https://ClinicalTrials.gov/show/NCT02835157 Completed All India Institute of Medical Sciences, New Delhi 2019-10-15
NCT02820987 PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock https://ClinicalTrials.gov/show/NCT02820987 Recruiting Centre Hospitalier Universitaire de Besancon 2016-09-01
NCT02805049 Pharmacokinetic Study on Echinocandins for Patients With Septic Shock Following Secondary Peritonitis https://ClinicalTrials.gov/show/NCT02805049 Completed Centre Hospitalier Universitaire de Nīmes 2018-06-23
NCT02763631 Symptomatic Treatment of Excessive Dynamic Airway Collapse Using Daytime Portable Continuous Positive Airway Pressure https://ClinicalTrials.gov/show/NCT02763631 Completed Guy’s and St Thomas’ NHS Foundation Trust 2017-06-14
NCT02748382 Fluids in Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02748382 Completed McMaster University 2017-08-19
NCT02736812 Pre-hospital Administration of Lyophilized Plasma for Post-traumatic Coagulopathy Treatment (PREHO-PLYO) https://ClinicalTrials.gov/show/NCT02736812 Completed French Defence Health Service 2019-10-31
NCT02730624 Piperacillin/Tazobactam in Critically Ill Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02730624 Completed Prince of Songkla University 2016-05-31
NCT02726776 Suspension Syndrome https://ClinicalTrials.gov/show/NCT02726776 Completed Institute of Mountain Emergency Medicine 2015-11-30
NCT02681653 Study the Impact of Statins in Septic Shock https://ClinicalTrials.gov/show/NCT02681653 Completed Sanjay Gandhi Postgraduate Institute of Medical Sciences 2014-10-31
NCT02666404 Impact of Amount of Fluid for Circulatory Resuscitation on Renal Function in Patients in Shock https://ClinicalTrials.gov/show/NCT02666404 Recruiting University Hospital, Basel, Switzerland 2020-12-31
NCT02664753 L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury https://ClinicalTrials.gov/show/NCT02664753 Recruiting Centre Hospitalier Universitaire de Nīmes 2021-03-31
NCT02655133 Effects on Microcirculation of IgGAM in Severe Septic/Septic Shock Patients. https://ClinicalTrials.gov/show/NCT02655133 Completed Università Politecnica delle Marche 2018-01-01
NCT02647554 Ulinastatin Treatment in Adult Patients With Sepsis and Septic Shock in China https://ClinicalTrials.gov/show/NCT02647554 Recruiting Peking Union Medical College Hospital 2020-05-31
NCT02645851 RApid Fluid Volume EXpansion in Patients in Shock After the Initial Phase of Resuscitation. https://ClinicalTrials.gov/show/NCT02645851 Recruiting Centre Hospitalier Régional d’Orléans 2021-11-16
NCT02638545 Hemodynamic Effects of Dexmedetomidine in Septic Shock https://ClinicalTrials.gov/show/NCT02638545 Completed University of Roma La Sapienza 2017-01-31
NCT02635854 Study of Platelet Activation in Septic Shock Patients https://ClinicalTrials.gov/show/NCT02635854 Completed University Hospital, Toulouse 2017-01-31
NCT02600312 Comparing Cytokines, Toxins Adsorbing oXiris Filter to ST150 Filter During CRRT in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT02600312 Completed Skane University Hospital 2018-01-31
NCT02596984 Evaluation of the Pharmacokinetics of Caspofungin in ICU Patients https://ClinicalTrials.gov/show/NCT02596984 Completed Centre Hospitalier Universitaire de Saint Etienne 2018-05-31
NCT02591771 Study of Multistep Pharmacological and Invasive Management for Cardiogenic Shock https://ClinicalTrials.gov/show/NCT02591771 Completed Niguarda Hospital 2017-07-25
NCT02814708 Clinical Trial of the BioMed rTSST‐1 Variant Vaccine in Healthy Adults https://ClinicalTrials.gov/show/NCT02814708 Active, not recruiting Biomedizinische Forschungs gmbH 2020-09-30
NCT02566460 The Effect of Lactate Clearance Oriented Haemodynamic Therapy on the Outcome of Patients With Septic Shock https://ClinicalTrials.gov/show/NCT02566460 Completed Peking Union Medical College Hospital 2014-12-31
NCT02519699 Microcirculation After MAP Increase in Septic Shock Patients With Previous Hypertension https://ClinicalTrials.gov/show/NCT02519699 Completed Federal University of São Paulo 2016-11-30
NCT02473718 Fluid Balance in the ICU - Interventions to Minimize Fluids in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT02473718 Completed Washington University School of Medicine 2014-12-31
NCT02473263 Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock https://ClinicalTrials.gov/show/NCT02473263 Active, not recruiting Assistance Publique - Hôpitaux de Paris 2019-02-09
NCT02453425 The Effects of Blood Pressure on Renal Function and Oxygenation in Septic Shock https://ClinicalTrials.gov/show/NCT02453425 Completed Sahlgrenska University Hospital, Sweden 2017-03-31
NCT02424136 PEAnut Anaphylaxis Predictors https://ClinicalTrials.gov/show/NCT02424136 Completed John Hunter Children’s Hospital 2018-08-28
NCT02421484 Cellular Immunotherapy for Septic Shock: A Phase I Trial https://ClinicalTrials.gov/show/NCT02421484 Completed Ottawa Hospital Research Institute 2016-06-30
NCT02369900 Esmolol to Treat the Hemodynamic Effects of Septic Shock https://ClinicalTrials.gov/show/NCT02369900 Completed Beth Israel Deaconess Medical Center 2019-12-31
NCT02354742 Echo vs. EGDT in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02354742 Completed Intermountain Health Care, Inc. 2017-05-31
NCT02340338 rTSST-1 Variant Vaccine Phase 1 First-in-man Trail https://ClinicalTrials.gov/show/NCT02340338 Completed Biomedizinische Forschungs gmbH 2015-06-30
NCT02338843 A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension https://ClinicalTrials.gov/show/NCT02338843 Completed La Jolla Pharmaceutical Company 2016-12-01
NCT02304939 CHangeovers of Norepinephrine in Intensive Care https://ClinicalTrials.gov/show/NCT02304939 Active, not recruiting University Hospital, Angers 2017-05-31
NCT02301819 ExtraCorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock https://ClinicalTrials.gov/show/NCT02301819 Recruiting Na Homolce Hospital 2020-06-30
NCT04173221 Direct Assessment of Microcirculation In Shock (DAMIS) https://ClinicalTrials.gov/show/NCT04173221 Recruiting Heinrich-Heine University, Duesseldorf 2020-12-31
NCT02270281 Dexmedetomidine on Microcirculation in Septic Shock https://ClinicalTrials.gov/show/NCT02270281 Completed Southeast University, China 2016-12-31
NCT02266589 Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT02266589 Completed Nanjing PLA General Hospital 2013-10-31
NCT03333278 The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial https://ClinicalTrials.gov/show/NCT03333278 Completed Australian and New Zealand Intensive Care Research Centre 2019-07-16
NCT02213796 Population Pharmacokinetics and Monte Carlo Dosing Simulations of Meropenem During the Early Phase of Severe Sepsis and Septic Shock in Critically Ill Patients in Intensive Care Units https://ClinicalTrials.gov/show/NCT02213796 Completed Prince of Songkla University 2013-12-31
NCT02188589 Evaluation of an Absorbable Implant for the Treatment of Nasal Valve Collapse https://ClinicalTrials.gov/show/NCT02188589 Completed Spirox, Inc. 2015-12-31
NCT02135770 Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Sepsis https://ClinicalTrials.gov/show/NCT02135770 Completed Indonesia University 2014-06-30
NCT02120404 Pilot Phase II Study: Hemodynamic Tolerance and Anti-inflammatory Effects of Esmolol During the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT02120404 Recruiting Assistance Publique - Hôpitaux de Paris 2020-09-30
NCT02118467 Vasoactive Drugs in Intensive Care Unit https://ClinicalTrials.gov/show/NCT02118467 Recruiting University of Chicago 2020-12-31
NCT02114710 Effects of Stress Doses of Hydrocortisone on Coagulation Dysfunction in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT02114710 Completed Nanjing PLA General Hospital 2012-10-31
NCT02085291 Effect of Different Strategies for Titrating a High MAP on Microcirculation https://ClinicalTrials.gov/show/NCT02085291 Completed Southeast University, China 2016-09-30
NCT02079402 Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care https://ClinicalTrials.gov/show/NCT02079402 Completed Scandinavian Critical Care Trials Group 2015-11-30
NCT02071290 Effect of Remote Ischemic Conditioning on Trauma Patients With Hemorrhagic Shock https://ClinicalTrials.gov/show/NCT02071290 Completed St. Michael’s Hospital, Toronto 2017-01-31
NCT01310790 Strategy of Early Improvement of Tissue Oxygenation Decrease the Mortality of Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01310790 Completed Chinese Septic Shock Network 2009-10-31
NCT01284452 Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) https://ClinicalTrials.gov/show/NCT01284452 Completed Mahidol University 2014-12-31
NCT01271153 Effects of Dobutamine on Microcirculation, Regional and Peripheral Perfusion in Septic Shock Patients https://ClinicalTrials.gov/show/NCT01271153 Completed Pontificia Universidad Catolica de Chile 2013-01-31
NCT02050269 Measuring the Plasma Clearance of Iohexol to Estimate Glomerular Filtration Rate in Intensive Care Unit Patients: Preliminary Feasibility Study https://ClinicalTrials.gov/show/NCT02050269 Completed University Hospital, Tours 2016-06-30
NCT02044159 Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study https://ClinicalTrials.gov/show/NCT02044159 Completed Children’s Hospital of Eastern Ontario 2016-04-30
NCT04451798 Acute Impact of the Impella CP Assist Device in Pts. With Cardiogenic Shock on the Patients Hemodynamic https://ClinicalTrials.gov/show/NCT04451798 Recruiting University of Leipzig 2021-12-31
NCT01988428 Prehospital Antibiotics Against Sepsis Trial https://ClinicalTrials.gov/show/NCT01988428 Completed VU University Medical Center 2017-06-30
NCT01973907 Pilot Study for the SQUEEZE Trial https://ClinicalTrials.gov/show/NCT01973907 Completed McMaster Children’s Hospital 2016-06-30
NCT01972828 Early Haemodynamic Optimization Using Preload Dependence During Septic Shock = EHOSS-1 https://ClinicalTrials.gov/show/NCT01972828 Completed Hospices Civils de Lyon 2013-08-31
NCT01948778 The Effects of a Polyethyleneimine-coated Membrane (oXirisâ„¢) for Hemofiltration Versus Polymyxin B- Immobilized Fibre Column (Toraymyxinâ„¢) for Hemoperfusion on Endotoxin Activity and Inflammatory Conditions in Septic Shock- A Randomized Controlled Pilot Study (ENDoX-study) https://ClinicalTrials.gov/show/NCT01948778 Completed University of Zurich 2019-05-31
NCT01945983 Early Use of Norepinephrine in Septic Shock Resuscitation https://ClinicalTrials.gov/show/NCT01945983 Completed Mahidol University 2017-08-31
NCT01927549 Culprit Lesion Only PCI Versus Multivessel PCI in Cardiogenic Shock https://ClinicalTrials.gov/show/NCT01927549 Completed University of Luebeck 2017-07-31
NCT01890317 Mild Hypothermia in Cardiogenic Shock Complicating Myocardial Infarction https://ClinicalTrials.gov/show/NCT01890317 Completed University of Leipzig 2015-11-30
NCT03637205 Extracorporeal Life Support in Cardiogenic Shock https://ClinicalTrials.gov/show/NCT03637205 Recruiting Leipzig Heart Institute GmbH 2022-09-30
NCT01850017 Study of Dexmedetomidine in Spine Surgery https://ClinicalTrials.gov/show/NCT01850017 Completed University of Virginia 2015-05-31
NCT01836224 Efficacy and Safety of Monotherapy With Noradrenaline and Terlipressin in Patients of Cirrhosis With Septic Shock Admitted to Intensive Care Unit https://ClinicalTrials.gov/show/NCT01836224 Completed Institute of Liver and Biliary Sciences, India 2014-09-30
NCT01827007 Assessment of Fluid Responsiveness by Elevation of PEEP in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT01827007 Completed Helsinki University Central Hospital 2012-12-31
NCT01818427 PreHospital Air Medical Plasma Trial https://ClinicalTrials.gov/show/NCT01818427 Completed University of Pittsburgh 2017-09-30
NCT01774214 Pediatric Fast Fluid Trial 2 https://ClinicalTrials.gov/show/NCT01774214 Completed McMaster Children’s Hospital 2013-05-31
NCT02025127 A Randomized Controlled Study of Enteral Nutrition in Septic Shock https://ClinicalTrials.gov/show/NCT02025127 Completed Medical College of Wisconsin 2018-01-31
NCT01718613 Vasopressin Versus Norepinephrine for the Management of Septic Shock in Cancer Patients https://ClinicalTrials.gov/show/NCT01718613 Completed Instituto do Cancer do Estado de São Paulo 2014-03-31
NCT04110418 Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonate https://ClinicalTrials.gov/show/NCT04110418 Recruiting Ain Shams University 2020-02-19
NCT01648036 Heparin Anticoagulation to Improve Outcomes in Septic Shock: The HALO Pilot https://ClinicalTrials.gov/show/NCT01648036 Completed University of Manitoba 2014-01-31
NCT01633502 Danish Cardiogenic Shock Trial https://ClinicalTrials.gov/show/NCT01633502 Recruiting Odense University Hospital 2022-09-30
NCT01630577 Central Venous Pressure Change With Volume Challenge in Patients With Hemodynamic Instability https://ClinicalTrials.gov/show/NCT01630577 Completed University of Monastir 2013-04-30
NCT01618396 Effects of Sedatives on Sublingual Microcirculation of Patients With Septic Shock https://ClinicalTrials.gov/show/NCT01618396 Completed Casa de Saúde São José 2011-08-31
NCT01615263 Lung Collapse With Bronchial Blocker https://ClinicalTrials.gov/show/NCT01615263 Completed Laval University 2012-10-31
NCT01612676 Investigating FE 202158 as Potential Primary Treatment in Patients With Early Septic Shock https://ClinicalTrials.gov/show/NCT01612676 Completed Ferring Pharmaceuticals 2013-11-30
NCT01611935 AVERT Shock: Arginine Vasopressin During the Early Resuscitation of Traumatic Shock https://ClinicalTrials.gov/show/NCT01611935 Completed University of Pennsylvania 2016-09-06
NCT01611753 Red Blood Cell Transfusion Improves Perfusion Parameters in Septic Shock Patients With Hypoperfusion https://ClinicalTrials.gov/show/NCT01611753 Completed Federal University of São Paulo 2008-08-31
NCT03314519 Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube https://ClinicalTrials.gov/show/NCT03314519 Completed Mahidol University 2019-07-10
NCT01526382 Use of PiCCO System in Critically Ill Patients With Septic Shock and Acute Respiratory Distress Syndrome https://ClinicalTrials.gov/show/NCT01526382 Completed Jinhua Central Hospital 2014-06-30
NCT01485315 Transfusion-requirements in Septic Shock Trial https://ClinicalTrials.gov/show/NCT01485315 Completed Scandinavian Critical Care Trials Group 2014-03-31
NCT01473498 Personalized Mean Arterial Pressure Management on Renal Function During Septic Shock https://ClinicalTrials.gov/show/NCT01473498 Completed Assistance Publique - Hôpitaux de Paris 2015-10-31
NCT01448109 ADjunctive coRticosteroid trEatment iN criticAlly ilL Patients With Septic Shock https://ClinicalTrials.gov/show/NCT01448109 Completed The George Institute 2017-10-22
NCT01443494 High MAP in Septic Shock With Hypertension https://ClinicalTrials.gov/show/NCT01443494 Completed Southeast University, China 2012-06-30
NCT01433276 Efficacy, Safety of Solution Containing Hyperosmolar Sodium Lactate Infusion for Resuscitation of Patients With Hemorrhagic Shock https://ClinicalTrials.gov/show/NCT01433276 Completed Innogene Kalbiotech Pte. Ltd 2011-01-31
NCT01411852 Field Trial of Hypotensive Versus Standard Resuscitation for Hemorrhagic Shock After Trauma https://ClinicalTrials.gov/show/NCT01411852 Completed University of Washington 2013-04-30
NCT01411670 Administration of Human Protein C Concentrates in Patients With Sepsis and Septic Shock. https://ClinicalTrials.gov/show/NCT01411670 Completed University of Roma La Sapienza 2015-02-28
NCT01393782 Intravenous AII for the Treatment of Severe Hypotension in High Output Shock: A Pilot Study https://ClinicalTrials.gov/show/NCT01393782 Completed George Washington University 2014-01-31
NCT03788837 Ilomedin in Septic Shock With Persistent Microperfusion Defects (I-MICRO) https://ClinicalTrials.gov/show/NCT03788837 Recruiting Assistance Publique - Hôpitaux de Paris 2022-08-03
NCT01367743 Study Comparing the Efficacy and Tolerability of Epinephrine and Norepinephrine in Cardiogenic Shock https://ClinicalTrials.gov/show/NCT01367743 Completed Central Hospital, Nancy, France 2016-02-29
NCT01352182 Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01352182 Completed Children’s Hospital Medical Center, Cincinnati 2016-05-31
NCT03635840 The Effects of IABP Prior to Revascularization on Mortality of ACS Patients Complicated With Cardiogenic Shock https://ClinicalTrials.gov/show/NCT03635840 Recruiting Indonesia University 2019-12-04
NCT04446871 Methylene Blue in Early Septic Shock https://ClinicalTrials.gov/show/NCT04446871 Recruiting Hospital Civil de Guadalajara 2020-09-30
NCT04398069 Hemodynamic Optimisation Guided With Transcranial Doppler in Septic Shock https://ClinicalTrials.gov/show/NCT04398069 Recruiting Mongi Slim Hospital 2020-08-31
NCT04369573 Study on Early Intra-aortic Balloon Pump Placement in Acute Decompensated Heart Failure Complicated by Cardiogenic Shock https://ClinicalTrials.gov/show/NCT04369573 Recruiting Niguarda Hospital 2020-10-30
NCT04360304 Assessment of Agreement Between Two Measurement Methods of Left Ventricular Outflow Tract (LVOT) Velocity Time Integral (VTI) https://ClinicalTrials.gov/show/NCT04360304 Recruiting Centre Hospitalier Universitaire de Nīmes 2021-03-31
NCT04302584 Norepinephrine / Vasopressin Combination for Resuscitation in Septic Shock https://ClinicalTrials.gov/show/NCT04302584 Completed Ain Shams University 2019-01-05
NCT04290767 Brain Ultrasound With Contrast Microbubbles Injection in Shock Status https://ClinicalTrials.gov/show/NCT04290767 Recruiting Universitair Ziekenhuis Brussel 2022-12-31
NCT04281277 Relation Between Mean Arterial Pressure and Renal Resistive Index in the Early Phase of Septic Shock https://ClinicalTrials.gov/show/NCT04281277 Recruiting University Hospital, Angers 2025-01-15
NCT04259567 Improvement of Cerebrovascular Autoregulation in Patients With Septic Shock Due to Cytokine Elimination https://ClinicalTrials.gov/show/NCT04259567 Recruiting Johannes Gutenberg University Mainz 2021-12-31
NCT04257136 VBI-S for the Treatment of Hypotension in Hypovolemic Septic Shock Patients https://ClinicalTrials.gov/show/NCT04257136 Recruiting Vivacelle Bio 2020-12-31
NCT04231994 Therapeutic Plasmaexchange in Early Septic Shock https://ClinicalTrials.gov/show/NCT04231994 Recruiting Hannover Medical School 2020-06-01
NCT04178148 Personalized Dose Optimization of Amikacin Guided by Pharmacokinetic Modeling Software in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT04178148 Recruiting Centre Hospitalier Universitaire de Nīmes 2020-05-31
NCT04156451 Effect of Fluid Deresuscitation With Central Venous Pressure Target 0-4 mmHg in Septic Shock Patients https://ClinicalTrials.gov/show/NCT04156451 Recruiting Indonesia University 2020-06-30
NCT04134624 EMS Prehospital Blood Culture Collection and Antibiotic Administration: A Two-Phase Pilot Project to Reduce Mortality in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04134624 Enrolling by invitation HealthPartners Institute 2021-01-31
NCT04130230 Adjuvant Use of Neostigmine in Sepsis and Septic Shock. https://ClinicalTrials.gov/show/NCT04130230 Recruiting Mansoura University 2020-03-31
NCT04123444 Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in Patients With Septic Shock Suffering From Organ Failure https://ClinicalTrials.gov/show/NCT04123444 Recruiting Rigshospitalet, Denmark 2022-09-30
NCT04111822 Pilot Study on the Use of Hydrocortisone, Vitamin c and Tiamine in Patient With Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT04111822 Recruiting Institut d’Investigació Biomèdica de Girona Dr. Josep Trueta 2020-10-31
NCT04107402 PLatelets Acetyl-CoA Carboxylase Phosphorylation State in SEPtic Shock https://ClinicalTrials.gov/show/NCT04107402 Recruiting Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2021-03-15
NCT04089072 Methylene Blue as a Third-line Vasopressor in Septic Shock https://ClinicalTrials.gov/show/NCT04089072 Recruiting Carilion Clinic 2021-10-01
NCT04056065 PMZ-2010 (Centhaquine) as a Resuscitative Agent for Hypovolemic Shock https://ClinicalTrials.gov/show/NCT04056065 Completed Pharmazz, Inc. 2018-09-19
NCT04055909 Efficacy, Safety and Tolerability of Nangibotide in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT04055909 Recruiting Inotrem 2021-04-30
NCT04045327 Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock https://ClinicalTrials.gov/show/NCT04045327 Completed Pharmazz, Inc. 2019-09-23
NCT04037644 Volume Expansion With Albumin vs. Crystalloid and Expiratory Lung Impedance https://ClinicalTrials.gov/show/NCT04037644 Recruiting University of Milan 2020-12-31
NCT04013269 Adjuvant Therapy With CytoSorb in Refractory Septic Shock https://ClinicalTrials.gov/show/NCT04013269 Recruiting Universitätsklinikum Hamburg-Eppendorf 2021-12-31
NCT03989609 Dexmedetomidine in Modifying Immune Paralysis In Patient With Septic Shock https://ClinicalTrials.gov/show/NCT03989609 Recruiting Kasr El Aini Hospital 2020-02-20
NCT03989531 Adrecizumab in Cardiogenic Shock https://ClinicalTrials.gov/show/NCT03989531 Recruiting Universitätsklinikum Hamburg-Eppendorf 2020-03-31
NCT03974386 Effects of Endotoxin Absorption and Cytokine Removal Hemofilter on Severe Septic Shock https://ClinicalTrials.gov/show/NCT03974386 Recruiting National Taiwan University Hospital 2020-09-30
NCT03953677 Evaluation of the Effect of Dexmedetomidine on Phenylephrine Response During Refractory Septic Shock https://ClinicalTrials.gov/show/NCT03953677 Recruiting Centre Hospitalier Universitaire Dijon 2021-04-30
NCT03898674 Microcirculatory Guided Goal Directed Fluid Therapy in Septic Shock; a Feasibility Study https://ClinicalTrials.gov/show/NCT03898674 Recruiting King’s College London 2020-10-01
NCT03869385 Albumin Replacement Therapy in Septic Shock https://ClinicalTrials.gov/show/NCT03869385 Recruiting Jena University Hospital 2021-07-21
NCT03866083 Safety and Efficacy of Extracorporeal Cytokine Hemoadsorption in Septic Shock in Critically Ill Cirrhotics https://ClinicalTrials.gov/show/NCT03866083 Recruiting Institute of Liver and Biliary Sciences, India 2019-06-30
NCT03844984 Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients https://ClinicalTrials.gov/show/NCT03844984 Completed Cairo University 2019-09-20
NCT03837171 TRANSfusion in Patients With Onco-hematological Malignancies ResusciTated From Septic Shock https://ClinicalTrials.gov/show/NCT03837171 Recruiting Assistance Publique - Hôpitaux de Paris 2021-02-20
NCT03835286 Vitamin C to Reduce Vasopressor Dose in Septic Shock https://ClinicalTrials.gov/show/NCT03835286 Recruiting Hospital Español de Mexico 2020-04-30
NCT03787732 Preventing Cardiovascular Collapse With Administration of Fluid Resuscitation During Induction and Intubation https://ClinicalTrials.gov/show/NCT03787732 Recruiting Vanderbilt University Medical Center 2021-01-31
NCT03783091 A Trial of Vitamin B12 in Septic Shock https://ClinicalTrials.gov/show/NCT03783091 Recruiting Medical College of Wisconsin 2023-12-31
NCT03773822 Low Dose of Hydrocortisone and Fludrocortisone in Adult Cardiogenic Shock. https://ClinicalTrials.gov/show/NCT03773822 Recruiting CMC Ambroise Paré 2021-04-20
NCT03765489 Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT03765489 Completed University of Chile 2018-06-21
NCT03762005 Peripheral Perfusion Versus Lactate Targeted Fluid Resuscitation in Septic Shock https://ClinicalTrials.gov/show/NCT03762005 Recruiting Pontificia Universidad Catolica de Chile 2019-09-30
NCT03756220 Ascorbic Acid and Thiamine Effect in Septic Shock https://ClinicalTrials.gov/show/NCT03756220 Recruiting Samsung Medical Center 2019-11-30
NCT03754257 Effects of High-frequency Electrical Stimulation for Preventing Loss of Muscle Mass in Patients With Sepsis https://ClinicalTrials.gov/show/NCT03754257 Recruiting Hospital Sirio-Libanes 2021-04-01
NCT03710187 HCT+F vs. HCT Alone in Critically Ill Medical Septic Shock Patients https://ClinicalTrials.gov/show/NCT03710187 Completed University of Tennessee Medical Center 2019-09-27
NCT03706053 Midodrine Use in Septic Shock https://ClinicalTrials.gov/show/NCT03706053 Recruiting University of Virginia 2020-03-31
NCT03680963 Early Versus Differed Arterial Catheterization in Critically Ill Patients With Acute Circulatory Failure: https://ClinicalTrials.gov/show/NCT03680963 Recruiting University Hospital, Tours 2021-11-30
NCT03668236 The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial https://ClinicalTrials.gov/show/NCT03668236 Recruiting Scandinavian Critical Care Trials Group 2020-11-30
NCT03661268 The Effect of Rapid Fluid Challenge Under Pulmonary Artery Catheter Monitoring on Physiological Indexes of Patients With Septic Shock https://ClinicalTrials.gov/show/NCT03661268 Recruiting Chengdu Fifth People’s Hospital 2019-09-30
NCT03654001 ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED) https://ClinicalTrials.gov/show/NCT03654001 Recruiting Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2020-12-31
NCT03623529 A Study of LJPC-501 in Paediatric Patients With Hypotension Associated With Distributive or Vasodilatory Shock https://ClinicalTrials.gov/show/NCT03623529 Recruiting La Jolla Pharmaceutical Company 2023-03-31
NCT03608514 Terlipressin Alone Versus the Standard Therapy With Catecholamines for Hepatic Patients With Septic Shock- Prospective Single Center Randomized Controlled Study. https://ClinicalTrials.gov/show/NCT03608514 Recruiting National Hepatology & Tropical Medicine Research Institute 2020-07-31
NCT03592693 Vitamin C, Hydrocortisone and Thiamine for Septic Shock https://ClinicalTrials.gov/show/NCT03592693 Recruiting University of Athens 2020-07-31
NCT03573739 Impact of Early Low-Calorie Low-Protein Versus Standard Feeding on Outcomes of Ventilated Adults With Shock https://ClinicalTrials.gov/show/NCT03573739 Recruiting Nantes University Hospital 2020-12-31
NCT03557229 Clinical Trial of Antioxidant Therapy in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT03557229 Recruiting American British Cowdray Medical Center 2020-06-30
NCT03551964 Dual Antiplatelet Therapy For Shock Patients With Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT03551964 Recruiting Faculty Hospital Kralovske Vinohrady 2020-06-30
NCT03530046 High Strong Ion Difference Fluid vs Hartmann’s Solution on Acid-Base Status in Sepsis https://ClinicalTrials.gov/show/NCT03530046 Completed Clinical Research Centre, Malaysia 2017-12-18
NCT03528213 Utility of Sodium Lactate Infusion During Septic Shock https://ClinicalTrials.gov/show/NCT03528213 Recruiting University Hospital, Lille 2021-11-30
NCT03523221 Use of Dexamethasone in Prevention of the Second Phase or a Biphasic Reaction of Anaphylaxis https://ClinicalTrials.gov/show/NCT03523221 Recruiting Hamad Medical Corporation 2020-04-30
NCT03487315 Major Allergen in Wheat Anaphylaxis in Thai Population https://ClinicalTrials.gov/show/NCT03487315 Completed Mahidol University 2018-03-05
NCT03480555 Replacing Protein Via Enteral Nutrition in a Stepwise Approach in Critically Ill Patients https://ClinicalTrials.gov/show/NCT03480555 Completed King Abdullah International Medical Research Center 2019-05-10
NCT03461900 Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock https://ClinicalTrials.gov/show/NCT03461900 Recruiting University Hospital, Brest 2023-01-31
NCT03461094 Fluid Responsiveness Evaluation in Patients With Acute Circulatory Failure and Arrhythmia With Atrial Fibrillation: Indice Delta ITV / Delta RR https://ClinicalTrials.gov/show/NCT03461094 Completed Poitiers University Hospital 2020-06-12
NCT03431467 Impella CP With VA ECMO for Cardiogenic Shock https://ClinicalTrials.gov/show/NCT03431467 Recruiting University of Pennsylvania 2021-01-01
NCT03431077 A Study of LJPC‑501 in Pediatric Patients With Hypotension https://ClinicalTrials.gov/show/NCT03431077 Completed La Jolla Pharmaceutical Company 2018-04-14
NCT01263977 Thermodilution - Controlled Management of Volume Therapy in Septic Shock https://ClinicalTrials.gov/show/NCT01263977 Completed Charite University, Berlin, Germany 2014-05-31
NCT01231698 Heart Rate Control With Esmolol in Septic Shock https://ClinicalTrials.gov/show/NCT01231698 Completed University of Roma La Sapienza 2012-07-31
NCT01222663 Effects of Hemoperfusion With a Polymyxin B Membrane in Peritonitis With Septic Shock https://ClinicalTrials.gov/show/NCT01222663 Completed Meditor SAS 2013-04-30
NCT01188993 Transpulmonary Thermodilution and Transesophageal Echocardiography in Early Septic Shock https://ClinicalTrials.gov/show/NCT01188993 Completed University Hospital, Limoges 2014-01-31
NCT01149278 Assessment of Two Levels of Arterial Pressure on Survival in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT01149278 Completed University Hospital, Angers 2012-09-30
NCT01145560 A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFabâ„¢) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock https://ClinicalTrials.gov/show/NCT01145560 Completed AstraZeneca 2012-05-31
NCT01144624 A Study to Assess Safety,and Tolerability of 2 Doses of AZD9773 (CytoFabâ„¢) in Japanese With Severe Sepsis/Septic Shock https://ClinicalTrials.gov/show/NCT01144624 Completed AstraZeneca 2011-08-31
NCT00279214 Hemodynamic and Perfusion Response to Drotrecogin Alfa (Activated) in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT00279214 Completed Eli Lilly and Company NA
NCT01077349 High Volume Veno-venous Hemofiltration Versus Standard Care for Post-cardiac Surgery Shock https://ClinicalTrials.gov/show/NCT01077349 Completed Assistance Publique - Hôpitaux de Paris 2013-01-31
NCT01070810 Thiamine as a Metabolic Resuscitator in Septic Shock https://ClinicalTrials.gov/show/NCT01070810 Completed Beth Israel Deaconess Medical Center 2014-11-30
NCT01046669 Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Septic Shock https://ClinicalTrials.gov/show/NCT01046669 Completed Spectral Diagnostics (US) Inc. 2016-07-31
NCT01013662 Lipid Profile in Patients With Severe Sepsis or Septic Shock Under Strict or Liberal Glycemic Control https://ClinicalTrials.gov/show/NCT01013662 Completed University of Sao Paulo 2007-07-31
NCT01000649 Effects of the V1a Agonist FE 202158 in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT01000649 Completed Ferring Pharmaceuticals 2011-08-31
NCT00995839 Terlipressin in Septic Shock: Effects on Microcirculation https://ClinicalTrials.gov/show/NCT00995839 Completed University of Roma La Sapienza 2010-02-28
NCT00974935 Phase I STEBVax in Healthy Adults https://ClinicalTrials.gov/show/NCT00974935 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2015-03-31
NCT00962156 Scandinavian Starch for Severe Sepsis/Septic Shock Trial https://ClinicalTrials.gov/show/NCT00962156 Completed Scandinavian Critical Care Trials Group 2012-03-31
NCT01004198 Phase IIa Study of MP4OX in Traumatic Hemorrhagic Shock Patients https://ClinicalTrials.gov/show/NCT01004198 Completed Sangart 2010-06-30
NCT00939900 Efficacy of Zoledronic Acid in Preventing Collapse of the Osteonecrotic Femoral Head https://ClinicalTrials.gov/show/NCT00939900 Completed Seoul National University Bundang Hospital 2012-06-30
NCT00930085 Evaluation of Predictive Proteic Profile on Mortality in the Acute Phase of Septic Shock in Cancer Patients https://ClinicalTrials.gov/show/NCT00930085 Completed Institut Paoli-Calmettes 2011-04-30
NCT00919685 Investigations of New Markers in Patients With Shock https://ClinicalTrials.gov/show/NCT00919685 Completed Assistance Publique Hopitaux De Marseille 2013-03-31
NCT00919178 Safety of and Immune Response to DEN4 Vaccine Component Candidate for Dengue Virus https://ClinicalTrials.gov/show/NCT00919178 Completed National Institute of Allergy and Infectious Diseases (NIAID) 2010-05-31
NCT00890162 A Randomized, Double-Blind, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis https://ClinicalTrials.gov/show/NCT00890162 Completed National Institutes of Health Clinical Center (CC) 2018-07-31
NCT03911817 Impact of Midodrine Administration on the Clinical Outcome of Septic Shock Patients https://ClinicalTrials.gov/show/NCT03911817 Completed Ain Shams University 2019-06-30
NCT03750253 Extracorporeal Shock Wave Therapy for Pain-Relief After Arthroscopy for Osteochondral Lesions of the Talus https://ClinicalTrials.gov/show/NCT03750253 Active, not recruiting Southwest Hospital, China 2019-02-01
NCT03457038 Use of Fc-MBL to Detect and Monitor the Presence of PAMPs During Septic Shock https://ClinicalTrials.gov/show/NCT03457038 Recruiting University Hospital, Toulouse 2019-07-18
NCT03813134 Testing the Value of Novel Strategy and Its Cost Efficacy in Order to Improve the Poor Outcomes in Cardiogenic Shock https://ClinicalTrials.gov/show/NCT03813134 Active, not recruiting University of Leicester 2023-03-03
NCT03649633 Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock https://ClinicalTrials.gov/show/NCT03649633 Recruiting University of Athens 2020-07-31
NCT03401398 Stress Hydrocortisone In Pediatric Septic Shock https://ClinicalTrials.gov/show/NCT03401398 Recruiting Seattle Children’s Hospital 2023-09-20
NCT04339868 Terlipressin for Refractory Septic Shock https://ClinicalTrials.gov/show/NCT04339868 Recruiting Mahidol University 2025-03-31
NCT03901807 Safety and Efficacy of Polymyxin B Hemoperfusion (PMX) for Endotoxemic Septic Shock in a Randomized, Open-Label Study https://ClinicalTrials.gov/show/NCT03901807 Recruiting Spectral Diagnostics (US) Inc. 2021-10-31
NCT03872011 Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT03872011 Recruiting Northern Jiangsu Province People’s Hospital 2020-07-01
NCT03700346 Muscle Lactate and Lactate to Pyruvate Ratio Clearance in Septic Shock Patients https://ClinicalTrials.gov/show/NCT03700346 Recruiting Military Hospital of Tunis 2018-10-30
NCT03582046 Targeting Abdominal Perfusion Pressure in Septic Shock https://ClinicalTrials.gov/show/NCT03582046 Recruiting Potrero Medical 2021-09-30
NCT03387605 Effect of Ivabradine in Stage D HF/Cardiogenic Shock Patients on Dobutamine https://ClinicalTrials.gov/show/NCT03387605 Recruiting Loyola University 2020-01-31
NCT02580240 Initiation of Hydrocortisone for the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT02580240 Completed Northern Jiangsu Province People’s Hospital 2016-09-30
NCT02579525 Targeted Tissue Perfusion Versus Macrocirculatory-guided Standard Care in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT02579525 Recruiting Helsinki University Central Hospital 2020-12-31
NCT02544594 Clinical Study of Extra-Corporal Life Support in Cardiogenic Shock Complicating Acute Myocardial Infarction https://ClinicalTrials.gov/show/NCT02544594 Completed Klinikum der Universitaet Muenchen 2018-03-31
NCT02336620 Balanced Salt Solution VS. Normal Saline Solution in Septic Shock https://ClinicalTrials.gov/show/NCT02336620 Completed Ramathibodi Hospital 2017-01-30
NCT04124809 Truth or Dare; Artificial Blastocoel Collapse Using Laser Before Blastocyst’s Vitrification Versus Non-laser Usage https://ClinicalTrials.gov/show/NCT04124809 Recruiting Benha University 2019-12-30
NCT03920982 Prognostic Value Serum Concentration of Indoxyl Sulfate During Acute Kidney Injury in Septic Shock Patients. https://ClinicalTrials.gov/show/NCT03920982 Recruiting Centre Hospitalier Universitaire, Amiens 2022-04-30
NCT00973102 Resuscitative Endocrinology: Single-dose Clinical Uses for Estrogen-Traumatic Hemorrhagic Shock (RESCUE - Shock) https://ClinicalTrials.gov/show/NCT00973102 Completed University of Texas Southwestern Medical Center 2012-01-31
NCT00763906 Norepinephrine Weaning in Septic Patients https://ClinicalTrials.gov/show/NCT00763906 Completed Association pour le Développement de la Recherche et de l’Enseignement en Médecine d’Urgence 2006-11-30
NCT00707122 Volume Replacement With Albumin in Severe Sepsis https://ClinicalTrials.gov/show/NCT00707122 Completed Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico 2013-04-30
NCT00639015 Phenylephrine in Septic Shock https://ClinicalTrials.gov/show/NCT00639015 Completed University of Roma La Sapienza 2008-06-30
NCT00628160 Terlipressin in Septic Shock in Cirrhosis https://ClinicalTrials.gov/show/NCT00628160 Completed Hospital Clinic of Barcelona 2012-12-31
NCT00629382 Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis https://ClinicalTrials.gov/show/NCT00629382 Completed St. Bortolo Hospital 2008-04-30
NCT00625209 Activated Protein C and Corticosteroids for Human Septic Shock https://ClinicalTrials.gov/show/NCT00625209 Completed University of Versailles 2015-06-30
NCT00800306 Effects of Levosimendan on Microcirculation in Septic Shock https://ClinicalTrials.gov/show/NCT00800306 Completed University of Roma La Sapienza 2008-02-29
NCT00604331 Effects of Pyruvate in Patients With Cardiogenic Shock and Intra-aortic Balloon Counterpulsation https://ClinicalTrials.gov/show/NCT00604331 Completed Herzzentrum Goettingen 2009-07-31
NCT00604019 Dopamine Versus Norepinephrine for the Treatment of Vasopressor Dependent Septic Shock https://ClinicalTrials.gov/show/NCT00604019 Completed Rush University Medical Center 2009-08-31
NCT01262196 Phase IIb Study of MP4OX in Traumatic Hemorrhagic Shock Patients https://ClinicalTrials.gov/show/NCT01262196 Completed Sangart 2012-10-31
NCT00592488 Acetyl-L-Carnitine in the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT00592488 Completed Vanderbilt University Medical Center 2009-08-31
NCT00534287 Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00534287 Completed Kompetenznetz Sepsis 2010-04-30
NCT00527007 External Cooling in Septic Shock Patients https://ClinicalTrials.gov/show/NCT00527007 Completed Assistance Publique - Hôpitaux de Paris 2010-03-31
NCT00510835 Protocolized Care for Early Septic Shock https://ClinicalTrials.gov/show/NCT00510835 Completed University of Pittsburgh 2013-07-31
NCT00491036 Intraaortic Balloon Pump in Cardiogenic Shock II https://ClinicalTrials.gov/show/NCT00491036 Completed University of Leipzig 2012-06-30
NCT00488462 Non-Pneumatic Anti-Shock Garment for Obstetrical Hemorrhage: Zambia and Zimbabwe https://ClinicalTrials.gov/show/NCT00488462 Completed University of California, San Francisco 2012-05-31
NCT00481572 Continuous Infusion of Terlipressin in Septic Shock https://ClinicalTrials.gov/show/NCT00481572 Completed University of Roma La Sapienza 2007-12-31
NCT00481442 Phenylephrine Versus Norepinephrine in Septic Shock https://ClinicalTrials.gov/show/NCT00481442 Completed University of Roma La Sapienza NA
NCT00469248 Aortic Balloon Counterpulastion in Myocardial Infarction Related Shock https://ClinicalTrials.gov/show/NCT00469248 Completed Martin-Luther-Universität Halle-Wittenberg NA
NCT00468858 A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children https://ClinicalTrials.gov/show/NCT00468858 Completed U.S. Army Medical Research and Development Command 2010-04-30
NCT00457613 Effects of Alkaline Phosphatase on Renal Function in Septic Patients https://ClinicalTrials.gov/show/NCT00457613 Completed Radboud University NA
NCT00420030 Abciximab in Patients Undergoing Percutaneous Coronary Intervention for Cardiogenic Shock https://ClinicalTrials.gov/show/NCT00420030 Completed Charles University, Czech Republic 2009-06-30
NCT00417378 Efficacy Study of LV Assist Device to Treat Patients With Cardiogenic Shock (ISAR-SHOCK) https://ClinicalTrials.gov/show/NCT00417378 Completed Deutsches Herzzentrum Muenchen NA
NCT00407823 Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring https://ClinicalTrials.gov/show/NCT00407823 Completed University of Sao Paulo NA
NCT00379522 Vasopressin in Traumatic Hemorrhagic Shock Study https://ClinicalTrials.gov/show/NCT00379522 Completed Medical University Innsbruck 2014-10-31
NCT00327704 Early Albumin Resuscitation During Septic Shock https://ClinicalTrials.gov/show/NCT00327704 Completed Laboratoire français de Fractionnement et de Biotechnologies 2010-06-30
NCT00320099 Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock https://ClinicalTrials.gov/show/NCT00320099 Completed University of Versailles 2009-01-31
NCT00314704 Dopamine and Norepinephrine in Shock Patients https://ClinicalTrials.gov/show/NCT00314704 Completed Sepsis Occurrence in Acutely Ill Patients 2007-10-31
NCT00305253 Efficacy Study of the Non-Pneumatic Anti-Shock Garment (NASG) in Egypt https://ClinicalTrials.gov/show/NCT00305253 Completed University of California, San Francisco 2008-06-30
NCT03788772 Systems Analysis of Antigen Presenting Cells in Human Sepsis https://ClinicalTrials.gov/show/NCT03788772 Recruiting Assistance Publique - Hôpitaux de Paris 2022-07-15
NCT00269685 Comparison of Vasopressin and Other Pressors in Septic Shock https://ClinicalTrials.gov/show/NCT00269685 Completed Université de Sherbrooke NA
NCT00241228 Haemofiltration Study : IVOIRE (hIgh VOlume in Intensive Care) https://ClinicalTrials.gov/show/NCT00241228 Completed University Hospital, Bordeaux 2010-10-31
NCT00207844 Selenium, as Sodium Selenite, in the Treatment of Septic Shock https://ClinicalTrials.gov/show/NCT00207844 Completed Centre Hospitalier de Meaux NA
NCT00197886 Dose of Norepinephrine and the Concentration of L-Lactate in the Rectum and Stomach in Patients With Septic Shock. https://ClinicalTrials.gov/show/NCT00197886 Completed Herlev Hospital NA
NCT00193986 Assessment of Prepulse Inhibition for Shock Pain Reduction https://ClinicalTrials.gov/show/NCT00193986 Completed University Health Network, Toronto NA
NCT00159952 Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00159952 Completed Policlinico Hospital 2007-03-31
NCT00148278 Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock https://ClinicalTrials.gov/show/NCT00148278 Completed University of Versailles 2004-12-31
NCT00147004 Corticosteroid Therapy of Septic Shock - Corticus https://ClinicalTrials.gov/show/NCT00147004 Completed Hadassah Medical Organization 2005-11-30
NCT00135473 Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) https://ClinicalTrials.gov/show/NCT00135473 Completed SepNet - Critical Care Trials Group NA
NCT00113685 Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury https://ClinicalTrials.gov/show/NCT00113685 Completed University of Washington NA
NCT00819416 Fluid Resuscitation in Early Septic Shock https://ClinicalTrials.gov/show/NCT00819416 Completed Ottawa Hospital Research Institute 2009-10-31
NCT00021502 Safety and Efficacy of PHP in the Treatment of Shock Associated With Systemic Inflammatory Response Syndrome (SIRS) https://ClinicalTrials.gov/show/NCT00021502 Completed Apex Bioscience 2003-08-31
NCT00134212 Dopexamine and Norepinephrine Compared With Epinephrine Alone in Septic Shock https://ClinicalTrials.gov/show/NCT00134212 Completed Rennes University Hospital NA
NCT00005890 Diagnostic Study of Adrenal Cortical Function in Children With Septic Shock https://ClinicalTrials.gov/show/NCT00005890 Completed National Center for Research Resources (NCRR) NA
NCT00000552 Shock Trial: Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock. https://ClinicalTrials.gov/show/NCT00000552 Completed HealthCore-NERI 2005-12-31

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT02248025 Can Capillary Refill Time Variation During Passive Leg Raising Predict Fluid Responsiveness https://ClinicalTrials.gov/show/NCT02248025 Completed Hopital Louis Pradel 2017-05-31
NCT03406598 Bedside Visual Analysis of Sublingual Microcirculation in Shock Patients https://ClinicalTrials.gov/show/NCT03406598 Recruiting Assistance Publique - Hôpitaux de Paris 2021-03-10
NCT03402035 Shock, Whole Blood, and Assessment of TBI S.W.A.T. (LITES TO 2) https://ClinicalTrials.gov/show/NCT03402035 Recruiting University of Pittsburgh 2022-02-01
NCT03953482 Evaluation of Medical Care and Patient’s Knowledge About the Behavior to Take on Secondary Prevention of Anaphylaxis https://ClinicalTrials.gov/show/NCT03953482 Active, not recruiting Groupe Hospitalier Paris Saint Joseph 2019-08-16
NCT03276364 The Impact of Point-of-Care Ultrasound https://ClinicalTrials.gov/show/NCT03276364 Completed Montefiore Medical Center 2015-04-17
NCT03190408 Variation in Fluids Administered in Shock https://ClinicalTrials.gov/show/NCT03190408 Completed Montefiore Medical Center 2018-02-01
NCT03184207 A Systematic Echography During Intubation Procedure to Predict Cardiovascular Collapse https://ClinicalTrials.gov/show/NCT03184207 Completed University Hospital, Brest 2017-06-21
NCT01867905 Antibiotic Administration and Blood Culture Positivity in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT01867905 Completed University of British Columbia 2018-09-05
NCT03104933 Proadrenomedullin and Copeptin in Patients With Septic Shock https://ClinicalTrials.gov/show/NCT03104933 Recruiting Spanish Network for Research in Infectious Diseases 2019-09-30
NCT03085459 Effects of Nursing Staff on Empiric Antibiotic in Septic Shock https://ClinicalTrials.gov/show/NCT03085459 Completed Southeast University, China 2016-02-29
NCT03082326 The CCUS Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value https://ClinicalTrials.gov/show/NCT03082326 Completed West China Hospital 2017-06-06
NCT03014063 Vasopressin Plasma Concentrations in Patients Receiving Exogenous Vasopressin Infusion for Septic Shock https://ClinicalTrials.gov/show/NCT03014063 Completed The Cleveland Clinic 2017-06-30
NCT02992002 Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography https://ClinicalTrials.gov/show/NCT02992002 Completed University of Schleswig-Holstein 2017-12-31
NCT01668329 Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis) https://ClinicalTrials.gov/show/NCT01668329 Completed University Hospital, Grenoble 2012-10-31
NCT02884011 Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic Shock https://ClinicalTrials.gov/show/NCT02884011 Completed Rush University Medical Center 2017-02-28
NCT02876341 Effects of Chronic Antihypertensive Therapy on Clinical Outcomes in Septic Shock https://ClinicalTrials.gov/show/NCT02876341 Completed Rush University Medical Center 2017-02-28
NCT02780466 Observational Study on Intubation in Septic Shock https://ClinicalTrials.gov/show/NCT02780466 Completed University Hospital, Angers 2017-10-31
NCT02772653 Evaluation of Resuscitation Markers in Trauma Patients https://ClinicalTrials.gov/show/NCT02772653 Completed Corporacion Parc Tauli 2019-03-26
NCT02750683 Norepinephrine Exerts an Inotropic Effect at the Early Phase of Human Septic Shock https://ClinicalTrials.gov/show/NCT02750683 Completed Hopital Antoine Beclere 2016-01-31
NCT02703038 French Observatory on the Management of Cardiogenic Shock in 2016 https://ClinicalTrials.gov/show/NCT02703038 Completed French Cardiology Society 2018-07-31
NCT02697006 Synchronized Cardiac Assist for Cardiogenic Shock https://ClinicalTrials.gov/show/NCT02697006 Active, not recruiting Xenios AG 2018-04-30
NCT02676427 Fluid Responsiveness in Septic Shock Evaluated by Caval Ultrasound Doppler Examination https://ClinicalTrials.gov/show/NCT02676427 Recruiting Charles University, Czech Republic 2021-05-31
NCT02584803 Inferior Vena Cava Assessment in Term Pregnancy Using Ultrasound: a Feasibility Study of Subxiphoid and RUQ Views https://ClinicalTrials.gov/show/NCT02584803 Completed Lawson Health Research Institute 2017-08-31
NCT02558166 Renal Resistive Index in Patients With Shock https://ClinicalTrials.gov/show/NCT02558166 Completed VU University Medical Center 2016-01-31
NCT02505646 Fluid Responsiveness Evaluation by AbdomiNal Compression in Kids Based on the STARLING Concept https://ClinicalTrials.gov/show/NCT02505646 Completed Hopital Louis Pradel 2016-12-31
NCT02393781 Adrenomedullin and Outcome in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02393781 Completed Sphingotec GmbH 2016-05-31
NCT02353910 VTE Incidence in Severe Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT02353910 Completed University of Utah 2014-12-31
NCT02306928 PK Analysis of Piperacillin in Septic Shock Patients https://ClinicalTrials.gov/show/NCT02306928 Completed University of Aarhus 2015-01-31
NCT02288975 Adsorbtion of Cytokines Early in Septic Shock: the ACESS Study https://ClinicalTrials.gov/show/NCT02288975 Completed Szeged University 2017-12-31
NCT02188888 Echocardiographic and Arterial Pressure Waveform Changes After Reducing Heart Rate With Esmolol in Septic Shock Patients https://ClinicalTrials.gov/show/NCT02188888 Completed University of Roma La Sapienza 2014-06-30
NCT02164851 Non-Invasive Shock: Differentiating Shock in the Emergency Department https://ClinicalTrials.gov/show/NCT02164851 Active, not recruiting Beth Israel Deaconess Medical Center 2021-01-31
NCT02164799 The Epidemiology and Approach to Differentiating Etiologies of Shock in the Emergency Department https://ClinicalTrials.gov/show/NCT02164799 Completed Beth Israel Deaconess Medical Center 2013-09-30
NCT02141607 Evolution of Molecular Biomarkers in Acute Heart Failure Induced by Shock https://ClinicalTrials.gov/show/NCT02141607 Completed Shockomics Consortium 2016-06-30
NCT02135796 Echocardiography in Septic Shock https://ClinicalTrials.gov/show/NCT02135796 Recruiting Intermountain Health Care, Inc. 2019-12-31
NCT02116413 Does the Time Between the End of Vascular Filling and Evaluation of Its Effectiveness Modify Fluid Challenge Results in Septic Shock? https://ClinicalTrials.gov/show/NCT02116413 Completed Centre Hospitalier Universitaire de Nīmes 2016-01-31
NCT02111109 An Observational Pilot Study of the Effects of Traumatic Haemorrhagic Shock and Resuscitation on the Microcirculation https://ClinicalTrials.gov/show/NCT02111109 Completed King’s College Hospital NHS Trust 2017-05-31
NCT02097212 Correlation Between Trachebroncho Malacia/Hyperdynamic Airway Collapse And Obstructive Sleep Apnea https://ClinicalTrials.gov/show/NCT02097212 Completed National Jewish Health 2015-03-31
NCT02083757 Fluid Responsiveness Predicted by PtcO2 in Critically Ill Patients https://ClinicalTrials.gov/show/NCT02083757 Completed Southeast University, China 2014-04-30
NCT02051894 NeoAdapt 3: Novel Biomarkers in the Evaluation of Neonatal Circulatory Insufficiency in Babies Suffering From Hypoxic Ischemic Encephalopathy https://ClinicalTrials.gov/show/NCT02051894 Completed Brighton and Sussex University Hospitals NHS Trust 2016-09-30
NCT02051855 NeoAdapt 2: An Observational Study Investigating Novel Biomarkers in the Evaluation and Treatment of Neonatal Circulatory Insufficiency https://ClinicalTrials.gov/show/NCT02051855 Completed Brighton and Sussex University Hospitals NHS Trust 2016-05-31
NCT02047916 NeoAdapt 1: A Study of Circulatory Adaptation of Newborn Infants After Birth https://ClinicalTrials.gov/show/NCT02047916 Completed Brighton and Sussex University Hospitals NHS Trust 2015-07-31
NCT02044575 Clock Genes in Patients With Refractory Septic Shock (SeptiClock) - Pilot Study https://ClinicalTrials.gov/show/NCT02044575 Completed Charite University, Berlin, Germany 2018-01-21
NCT01993745 The Analysis of Heart Rate Variability With 24hrs Holter ECG and Serum Cardiac Fibrosis Markers in Critical Illness Patients Who Are With Cardiogenic Shock, With ECMO or IABP Support, or With APACH II Score >25) https://ClinicalTrials.gov/show/NCT01993745 Completed National Taiwan University Hospital 2009-05-31
NCT01906775 Sub-threshold Pacing to Prevent Pacemaker-induced Ventricular Tachycardia https://ClinicalTrials.gov/show/NCT01906775 Completed Johannes Gutenberg University Mainz 2012-09-30
NCT01836302 Septic Shock and Delirium Because of rSO2 Abnormalities in Intensive Care Unit Patients (The SAD BRAIN Study) https://ClinicalTrials.gov/show/NCT01836302 Completed University of Manitoba 2013-12-31
NCT02652364 Strong Ion Gap as Prognostic Indicator for Adult Patients Admitted With Shock to the Intensive Care Units https://ClinicalTrials.gov/show/NCT02652364 Completed Singapore General Hospital 2017-10-31
NCT04089098 VOLume and Vasopressor Therapy in Patients With Hemodynamic instAbility https://ClinicalTrials.gov/show/NCT04089098 Recruiting University of Leipzig 2020-12-31
NCT01590511 Echocardiographic Prediction of Fluid Responsiveness After a Mini-fluid Challenge in Non-ventilated Patients With Shock https://ClinicalTrials.gov/show/NCT01590511 Completed Centre Hospitalier Universitaire de Nīmes 2015-12-31
NCT03313687 SafeTy and Outcome of contemPorary Treatment Strategies for Cardiogenic SHOCK https://ClinicalTrials.gov/show/NCT03313687 Recruiting Universitätsklinikum Hamburg-Eppendorf 2020-12-31
NCT01523717 Procalcitonin Monitoring Sepsis Study https://ClinicalTrials.gov/show/NCT01523717 Completed Brahms AG 2014-03-31
NCT01374867 CardShock Study and Registry https://ClinicalTrials.gov/show/NCT01374867 Completed Helsinki University Central Hospital 2013-12-31
NCT01363635 Severe Sepsis/Septic Shock on Admission to the General Surgical ICU https://ClinicalTrials.gov/show/NCT01363635 Completed Mahidol University 2019-01-31
NCT01319630 The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients https://ClinicalTrials.gov/show/NCT01319630 Completed Mercy Research 2013-12-31
NCT04388267 Fluid REsponsiveness and Arterial ELASTANCE in Patients With Septic Shock or After Aortic Surgery https://ClinicalTrials.gov/show/NCT04388267 Recruiting Central Hospital, Nancy, France 2020-06-30
NCT02924792 Sternal Intraosseous Transfusion of Autologous Whole Blood: A Comparison of Flow Rates and Degree of Hemolysis https://ClinicalTrials.gov/show/NCT02924792 Completed Haukeland University Hospital 2017-10-31
NCT04250389 Microcirculatory Effects of Methylene Blue https://ClinicalTrials.gov/show/NCT04250389 Completed Hospices Civils de Lyon 2017-01-01
NCT04202432 Clinical Validation of Algorithms for Mean Systemic Filling Pressure and Automated Cardiac Output https://ClinicalTrials.gov/show/NCT04202432 Completed Catharina Ziekenhuis Eindhoven 2019-08-30
NCT04153578 Time to Lose the Weight? Comparison of Weight-based and Non-weight-based Vasopressors for Septic Shock https://ClinicalTrials.gov/show/NCT04153578 Recruiting Methodist Health System 2020-11-30
NCT04141410 Global Longitudinal Strain Assessment in Cardiogenic Shock During Sepsis https://ClinicalTrials.gov/show/NCT04141410 Recruiting Azienda USL Toscana Centro 2020-10-21
NCT04079829 Postoperative Respiratory Abnormalities https://ClinicalTrials.gov/show/NCT04079829 Active, not recruiting Efficacy Care R&D Ltd 2020-10-31
NCT04067674 Septic Shock-induced Immunosuppression https://ClinicalTrials.gov/show/NCT04067674 Recruiting Hospices Civils de Lyon 2024-11-21
NCT04048837 Prospective Study for the Evaluation of Dengue Prognostic Biomarkers in Singapore https://ClinicalTrials.gov/show/NCT04048837 Completed National University Hospital, Singapore 2019-07-01
NCT04028297 Focus Cardiac Ultrasound in Patients With Shock https://ClinicalTrials.gov/show/NCT04028297 Recruiting Nantes University Hospital 2019-09-01
NCT04017923 Measurement of Age and Sex Related Changes in Nasal Tip Support Using Digital Newton Meter https://ClinicalTrials.gov/show/NCT04017923 Completed Baskent University Ankara Hospital 2019-05-01
NCT03987048 Cirrhotic Patients With Septic Shock https://ClinicalTrials.gov/show/NCT03987048 Completed Hospices Civils de Lyon 2015-04-30
NCT03977688 Evaluating a CytoSorb Score in Septic Shock https://ClinicalTrials.gov/show/NCT03977688 Completed Klinikum Emden 2019-05-30
NCT03942692 What is the Allergy Follow-up for Children After Anaphylactic Reaction? AFCAR : Allergy Follow-up for Children After Anaphylactic Reaction https://ClinicalTrials.gov/show/NCT03942692 Completed Hospices Civils de Lyon 2019-08-20
NCT03935477 Surrogate of Adequate Perfusion: Bladder Tissue Oxygen Monitoring https://ClinicalTrials.gov/show/NCT03935477 Recruiting University College London Hospitals 2020-02-29
NCT03917446 Volume Responsiveness Assesment After Propofol. https://ClinicalTrials.gov/show/NCT03917446 Recruiting Medical University of Gdansk 2019-09-03
NCT03913468 Outcomes of Septic Shock Patients Treated With a Metabolic Resuscitation Bundle Consisting of Intravenous Hydrocortisone, Ascorbic Acid and Thiamine. https://ClinicalTrials.gov/show/NCT03913468 Active, not recruiting University of Wisconsin, Madison 2021-01-01
NCT03873675 Parathyroid Hormone Kinetics During CRRT https://ClinicalTrials.gov/show/NCT03873675 Recruiting Uniwersytecki Szpital Kliniczny w Opolu 2020-04-01
NCT03814564 ASSESSment of Perfusion, Oxygen Saturation, Endothelial Function and Coagulation in Circulatory SHOCK https://ClinicalTrials.gov/show/NCT03814564 Recruiting Helsinki University Central Hospital 2021-10-31
NCT03713307 Macro and Micro Haemodynamic Responses to Shock in the Renal and Systemic - MICROSHOCK - RENAL https://ClinicalTrials.gov/show/NCT03713307 Recruiting King’s College London 2020-06-30
NCT03701646 ClearSight Validation in Pediatrics https://ClinicalTrials.gov/show/NCT03701646 Recruiting Nemours Children’s Clinic 2019-03-01
NCT03694717 Time Course Evolution of Cardiac Output https://ClinicalTrials.gov/show/NCT03694717 Completed Association pour le Développement et l’Organisation de la Recherche en Pneumologie et sur le Sommeil 2018-05-15
NCT03663192 Strain Echocardiography During Septic Shock : an Observational Pilot Study https://ClinicalTrials.gov/show/NCT03663192 Completed Centre Hospitalier Universitaire de Nīmes 2018-03-30
NCT03622099 Small Volume Fluid Challenge as a Predictor of Fluid Responsiveness in Patients With Circulatory Failure https://ClinicalTrials.gov/show/NCT03622099 Completed Menoufia University 2019-02-05
NCT03617965 Mortality Due to Septic Shock Associated With Thrombocytopenia https://ClinicalTrials.gov/show/NCT03617965 Active, not recruiting Universidad de Guanajuato 2019-11-15
NCT03596944 Primary Prevention With Statin and Incidence of Recurrent MI and Cardiogenic Shock in Post-ACS Patients https://ClinicalTrials.gov/show/NCT03596944 Completed Faculty of Medicine, Tarumanagara University 2018-06-30
NCT03559569 Impact of Endothelial and Leukocyte Senescence in Circulatory Shock States https://ClinicalTrials.gov/show/NCT03559569 Recruiting University Hospital, Strasbourg, France 2025-02-28
NCT03535441 HMGB1 Release From Hemorrhagic Shock Patients https://ClinicalTrials.gov/show/NCT03535441 Completed First People’s Hospital of Chenzhou 2018-04-11
NCT03472079 TIMP2*IGFBP7 and Transient AKI https://ClinicalTrials.gov/show/NCT03472079 Recruiting Centre Hospitalier Universitaire, Amiens 2019-07-01
NCT03456180 Changes in Microvascular Perfusion During Blood Purification With Cytosorb® in Septic Shock https://ClinicalTrials.gov/show/NCT03456180 Completed Università Politecnica delle Marche 2017-12-15
NCT03438097 Survey of Non-resuscitation Fluids in Septic Shock https://ClinicalTrials.gov/show/NCT03438097 Completed Region Skane 2018-07-30
NCT01231672 Prospective Validation of Clini-biological Parameters Including Initial Hemostasis, Which Improve the Prediction of Death at 1 Month Among Patients With Septic Shock https://ClinicalTrials.gov/show/NCT01231672 Completed Centre Hospitalier Universitaire de Nīmes 2013-10-31
NCT00900848 Posterior Tibial Artery Bypass for Iliofemoral Artery Injury Associated With Massive Blood Loss and Shock https://ClinicalTrials.gov/show/NCT00900848 Completed The Second Hospital of Qinhuangdao 2009-01-31
NCT00868842 Desensitization of Human Mast Cells: Mechanisms and Potential Utility for Preventing Anaphylaxis https://ClinicalTrials.gov/show/NCT00868842 Completed Virginia Commonwealth University 2012-05-31
NCT04231695 Extracorporeal Cytokine Removal in Patients With Septic Shock in an Adult Intensive Care Unit https://ClinicalTrials.gov/show/NCT04231695 Recruiting Hospital Jose Maria Cullen 2020-12-31
NCT02675725 Kinetics of the Sublingual Microcirculation During Fluid Bolus https://ClinicalTrials.gov/show/NCT02675725 Completed Medical Centre Leeuwarden 2018-02-15
NCT01981629 The Use of the USCOM Device in Addition to Cardiac Ultrasound in Patients Undergoing Treatment for Undifferentiated Shock https://ClinicalTrials.gov/show/NCT01981629 Completed Hennepin Healthcare Research Institute 2013-08-31
NCT01600989 Mitochondrial Function of Immune Cells in Sepsis https://ClinicalTrials.gov/show/NCT01600989 Completed University Hospital Inselspital, Berne 2013-10-31
NCT04366921 European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO https://ClinicalTrials.gov/show/NCT04366921 Recruiting Maastricht University Medical Center 2021-04-30
NCT04323709 Levosimendan for Veno-arterial ECMO Weaning https://ClinicalTrials.gov/show/NCT04323709 Completed Hospices Civils de Lyon 2019-01-31
NCT02918214 Prognostic Assessment of Diastolic and Systolic Left Ventricular Function in Septic Shock https://ClinicalTrials.gov/show/NCT02918214 Completed University Hospital, Limoges 2019-10-31
NCT00719719 Cause of Unexplained Anaphylaxis https://ClinicalTrials.gov/show/NCT00719719 Recruiting National Institutes of Health Clinical Center (CC) NA
NCT03952871 Value of Cardiac Output Monitoring by Supra-sternal Doppler/Echocardiography in Intensive Care Unit https://ClinicalTrials.gov/show/NCT03952871 Completed CHU de Reims 2019-04-24
NCT03136081 Candida Host Defense Response After Septic Shock in the Critically Ill https://ClinicalTrials.gov/show/NCT03136081 Completed University Hospital, Montpellier 2015-05-31
NCT02858115 Use of Mini-fluid Challenge for Fluid Responsiveness Prediction During One-lung Ventilation https://ClinicalTrials.gov/show/NCT02858115 Completed Assistance Publique Hopitaux De Marseille 2015-12-31
NCT01604551 Membrane Shedding During Septic Shock https://ClinicalTrials.gov/show/NCT01604551 Completed University Hospital, Strasbourg, France NA
NCT03716310 Platelet Reactivity in Septic Shock https://ClinicalTrials.gov/show/NCT03716310 Completed Università degli Studi di Ferrara 2018-05-30
NCT03210818 Effects of Blood Flow of Venoarterial Extracorporeal Membrane Oxygenation Life Support on Microcirculation https://ClinicalTrials.gov/show/NCT03210818 Completed National Taiwan University Hospital 2018-12-03
NCT00743522 Programming Implantable Cardioverter Defibrillators in Patients With Primary Prevention Indication https://ClinicalTrials.gov/show/NCT00743522 Completed Abbott Medical Devices 2011-09-30
NCT00736723 NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock https://ClinicalTrials.gov/show/NCT00736723 Completed University of Ulm 2012-08-31
NCT00713102 Surgical and Medical Emergencies on Board of European Aircraft Carriers https://ClinicalTrials.gov/show/NCT00713102 Completed Ruhr University of Bochum 2008-08-31
NCT00698048 Serial Vasopressin and Copeptin Levels in Children With Sepsis and Septic Shock https://ClinicalTrials.gov/show/NCT00698048 Completed KK Women’s and Children’s Hospital 2011-12-31
NCT00684736 Tryptophan, Serotonin and Kynurenine in Septic Shock https://ClinicalTrials.gov/show/NCT00684736 Completed Versailles Hospital 2007-04-30
NCT00523198 Correlation Salivary Cortisol and Free Serum Cortisol to Total Serum Cortisol in MICU Septic Shock https://ClinicalTrials.gov/show/NCT00523198 Completed The University of Texas Health Science Center, Houston 2008-08-31
NCT00118664 Patient Plasma Response and Outcome in Septic Shock With Thrombocytopenia Associated Multiple Organ Failure in Children https://ClinicalTrials.gov/show/NCT00118664 Completed Children’s Healthcare of Atlanta 2012-02-29
NCT00047918 Blood Factors in Mastocytosis and Unexplained Anaphylaxis and Flushing https://ClinicalTrials.gov/show/NCT00047918 Completed National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03475667 Comparison of Radial and Femoral Artery Site Invasive Blood Pressure Measurement in Septic Shock Patients https://ClinicalTrials.gov/show/NCT03475667 Completed Sanjay Gandhi Postgraduate Institute of Medical Sciences 2020-01-10
NCT03225378 Changes in PPV Induced by PLR Test to Predict Fluid Responsiveness in ICU https://ClinicalTrials.gov/show/NCT03225378 Recruiting Centre Hospitalier Arras 2020-09-30
NCT03182491 Mechanisms of Anaphylaxis https://ClinicalTrials.gov/show/NCT03182491 Active, not recruiting Haukeland University Hospital 2019-12-31
NCT03831022 Usefulness of Capillary Refill Time and Skin Mottling Score to Predict Intensive Care Unit Admission https://ClinicalTrials.gov/show/NCT03831022 Recruiting Hôpital Necker-Enfants Malades 2020-12-17
NCT01947127 Venous Lactate in Progression to Overt Septic Shock and Mortality in Non-elderly Sepsis Patients in Emergency Department https://ClinicalTrials.gov/show/NCT01947127 Completed Chulalongkorn University 2014-11-30
NCT03378739 Inova Cardiogenic Shock Registry (INOVA SHOCK) https://ClinicalTrials.gov/show/NCT03378739 Recruiting Inova Health Care Services 2020-05-29
NCT04429477 Cerebral Compliance Impairment in COVID-19 https://ClinicalTrials.gov/show/NCT04429477 Recruiting University of Sao Paulo 2020-07-15
NCT04357275 The RIsk Stratification in COVID-19 Patients in the ICU Registry https://ClinicalTrials.gov/show/NCT04357275 Recruiting University of Zurich 2021-03-31
NCT04143893 The Current Status and Clinical Outcomes of Patients With Cardiogenic Shock II https://ClinicalTrials.gov/show/NCT04143893 Recruiting Samsung Medical Center 2023-12-31
NCT04031794 ECMO for Critically Ill Patients With Respiratory Failure and/or Circulatory Failure https://ClinicalTrials.gov/show/NCT04031794 Recruiting Mahidol University 2025-07-30
NCT03677180 National Cardiogenic Shock Initiative https://ClinicalTrials.gov/show/NCT03677180 Recruiting Henry Ford Health System 2021-05-31